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BRAIN TUMORS (USMLE HIGH-YIELD) - Coggle Diagram
BRAIN TUMORS (USMLE HIGH-YIELD)
INTRA-AXIAL (Within Brain Parenchyma)
ASTROCYTIC TUMORS (GFAP+)
Glioblastoma (GBM): Adults, pseudopalisading necrosis, "butterfly glioma" crossing corpus callosum
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Low-Grade / Anaplastic Astrocytoma: Infiltrative astrocytic neoplasms
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Oligodendroglioma
Adults, usually frontal lobe
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"Fried-egg" cells and "chicken-wire" capillary pattern
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Ependymoma
Children, typically 4th ventricle
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Perivascular pseudorosettes, causes obstructive hydrocephalus
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Medulloblastoma (PNET)
Children, cerebellum / infratentorial
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Homer Wright rosettes, can spread via CSF (drop metastases)
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Primary CNS Lymphoma
Associated with immunocompromise / EBV
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Metastasis
Multiple lesions at gray-white matter junction (common from lung, breast, melanoma)
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EXTRA-AXIAL (Outside Brain Parenchyma)
Meningioma
Adult females, arises from arachnoid meningothelial cells
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Dural attachment ("tail"), psammoma bodies, benign compressive mass
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Acoustic Neuroma (Schwannoma)
Schwann cells, cerebellopontine angle (CN VIII)
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Tinnitus, sensorineural hearing loss, S100 positive
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Craniopharyngioma
Rathke's pouch remnant, supratentorial / sellar region
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Calcifications, cholesterol crystals ("motor oil" fluid), bitemporal hemianopia in children
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