Please enable JavaScript.

Coggle requires JavaScript to display documents.

Dietary triaclyglycerols, cholesterol esters, and phospholipids, Insulin…

- - - - Micelles → intestinal enterocytes → re-formed TAGs → chylomicrons → lymph → blood
      - Chylomicron TAGs → fatty acids for tissue uptake
      - Storage and mobilization
        
        Fatty-acid β-oxidation (Fatty acids → Acetyl-CoA + NADH + FADH₂ → ATP production)
        
        Cholesterol regulation
        
        Acetyl-CoA → Cholesterol
        
        Rate-limiting enzyme: HMG-CoA reductase
        
        Imbalance in cholesterol synthesis, intake, and utilization can contribute to atherosclerosis.
        
        Ketogenesis
        
        Acetyl-CoA in liver → Ketone bodies
        
        Increases during starvation and high fatty-acid mobilization
        
        Lipogenesis
        
        Excess energy → Fatty acids → TAG storage
        
        Excess energy → TAG storage in adipose tissue
        
        Stored TAGs → lipolysis → fatty acids + glycerol