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Antioxidants, Hemolytic Anaemia, Low stores of Vitamin D, pro-oxidants,…

- - - - nutritional imbalance
        
        oxidative stress
        
        become pro-oxidants under certain conditions
  - - - People at risk for lung cancer
        
        Higher incidence of lung cancer
    - - Male smokers
        
        Higher incidence of lung cancer
    - - Male aged 50+
        
        No prostate cancer prevention; Vitamin E alone linked to 17% increase in prostate cancer
  - - - Supplements can cause toxicity and act as harmful
      - Food Provides essential and natural antioxidant nutrient
- - - - 🌻Vitamin E
        
        Active form
        
        α-tocopherol
        
        Bioavailability
        
        20-70%
        
        Stored in
        
        in
        
        Adipose tissue (fat tissue)
        
        at
        
        90%
        
        Why we need it :!?:
        
        As an Antioxidant
        
        Donates H atom
        
        lipid radicals
        
        Chain Reaction stops :red_cross:
        
        Protects
        
        Cell membranes
        
        PUFA
        
        Mitochondria
        
        Nucleus and DNA
        
        Lungs
        
        other roles
        
        reduces
        
        platelet aggregation
        
        Heart Health :<3:
        
        Reproduction
        
        Sources :red_flag:
        
        Plant foods
        
        Nuts 🥜
        
        Hazelnut
        
        Almond
        
        Oils
        
        Safflower 🌼
        
        Wheatgerm 🌾
        
        Sunflower
        
        Seeds 🌱
        
        Sunflower🌻
        
        Pumpkin 🎃
        
        Sesame
        
        Animal foods
        
        Liver 🥩
        
        Egg yolk 🍳
        
        What if :!!:
        
        Too much
        
        How :!?:
        
        Supplements overconsumption
        
        if taken with
        
        1 more item...
        
        Symptoms
        
        3 more items...
        
        Too little
        
        Red Blood Cells burst :explode:
        
        Interaction
        
        is spared by
        
        Selenium
        
        In competition with
        
        🥕 β-Carotene
        
        is regenerated by
        
        Vitamin C
      - Absorbed with
        
        Dietary Fat
      - Risk of Toxicity :warning:
        
        If STORED excessively in the body
    - - Vitamin C
        
        Roles
        
        Antioxidant
        
        Reducing Agent
        
        Vitamin E regeneration
        
        Regenerating Vitamin E, H donated
        
        2 more items...
        
        Free Radical electron donation
        
        In and out of cells
        
        Non Antioxidant
        
        Collagen Synthesis
        
        Skin
        
        Connective tissue
        
        Gums
        
        Blood Vessels
        
        keeps folate intacts
        
        Converts Fe2+ to
        
        Found in
        
        Plants
        
        Fruits
        
        Kiwi
        
        Guava
        
        Tomatro
        
        Vegetabales
        
        broccoli
        
        peppers
        
        Forms
        
        Dehydroascorbic Acid
        
        Oxidized Form
        
        Absorbic Acid
        
        Reduced Form
        
        Functions
        
        Reducing Agent
        
        Destroyed by
        
        Heat
        
        oxidation
        
        absorption by starches
        
        too much
        
        Megadoses (10x DRI)
        
        Diarreah
        
        Iron Release
        
        oxidative damage to cells
        
        Pro oxidant
        
        symptoms
        
        Kidney Stones
        
        Rebound Scurvy
        
        no support
        
        cancer prevention
        
        limited evidence
        
        reducing effects of sickness prior to sickness
        
        Too little
        
        scurvy
        
        loose teeth
        
        impaired wound healing
        
        petechia
        
        at risk
        
        alcoholics
        
        smokers
        
        burn patients
        
        bleeding gums
      - Excess
        
        Excreted in unrie
  - - - unstable compunds
        
        chair reaction ends :red_cross:
- - - - unstable atoms/molecules
        
        unpaired electron
    - - external enviroment
        
        smoke
        
        UV Light
        
        Pollution
        
        Radiation
      - internal enviroment
        
        metabolism
        
        Immune Cells
        
        Making ATP
    - - DNA
      - Lipids
        
        Cell membrane
        
        LDL
      - Proteins
    - - Nitric Oxide (NO)
      - Superoxide (O2-)
      - hydroxyl radical (OH)
- - - - Placed in high-Oxygen incubators
        
        oxidative stress on Lung membranes
        
        oxidative stress compensation