Please enable JavaScript.

Coggle requires JavaScript to display documents.

Dermatology - Coggle Diagram

- - - - All age groups, even healthy patients
  - - - 2cm vertical incision made in affected skin and index finger is pushed into tissue
      - Test is positive if finger passes through the subcutaneous tissue without resistance
  - - - High mortality (up to 50%)
- - - - Carbamazepine
        
        Test for HLA-B*1502 before administering
    - - Allopurinol
- - - - Skin detachment between 10-30% of body surface area
      - Widespread purpuric macules or flat atypical targets
    - - Skin detachment < 10% of BSA
      - Widespread erythematous or purpuric macules
- - - - PD1 inhibitors
        
        Pembrolizumab
      - DPP-4 inhibitors
        
        Gliptin
    - - Mild cases
        
        Topical corticosteroids
        
        Antiseptics
      - Mild/moderate cases
        
        Systemic corticosteroids
        
        Doxycycline
      - Immunosuppression
        
        Mycophenolate mofetil
        
        Azathioprine
      - Infection
        
        Antibiotics
      - Severe / refractory
        
        IV immunoglobulins
  - - - Initial treatment
        
        Systemic corticosteroids
      - Long term control
        
        Immunosuppressive agents
        
        Mycophenolate mofetil
        
        Azathioprine
        
        Rituximab
      - Infection
        
        Antibiotics
      - Severe / refractory
        
        IV immunoglobulin
- - - - Skin lesions develop at peripheral before spreading centrally
      - 3 concentric rings of red lesions, surrounded by pallor erythema
      - Severe cases: blister or bullae