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Humanized Mouse Taxonomy - Coggle Diagram
Humanized Mouse Taxonomy
Genetic modification
Knockouts
MHC I/II KO
TLR4 KO
FcxR KO
Complement CS
Others
Model Type
HSC-Engrafted
PBMC-Engrafted
Dual-Engrafted
PDX Models
Pathogen-Engrafted
Others
Cytokine Transgene
IL-15 KI
IL-34 KI
Flt3L KI
IL-6 & TSLT
Knock-Ins
SCF/ GM-CSF/ CSF1
Others
Functional Application
CAR-T & GVD
PBMC Co-Engraftment
Dose Toxicity Assays
Humoral Immunity
Cellular Immunity
Others
HSC engraftment
Application areas
Oncology
Immunology
Infectious Disease
Metabolism
Neuroscience
Others