Please enable JavaScript.
Coggle requires JavaScript to display documents.
Acetyl-CoA, CITRIC ACID CYCLE, Aconitase, Isocitrate dehydrogenase, a-…
-
-
-
-
-
-
-
-
-
- Condensation of Acetyl CoA with
oxaloacetate to form citrate,
Catalyzed by citrate synthase enzyme
- Citrate is isomerized by
Dehydration and rehydration
To give isocitrate
- Isocitrate undergoes oxidation
and decarboxylation to give
a- Ketoglutarate and CO2
- oxidative decarboxylation occurs
In which a- Katoglutarate is
converted to Succinyl CoA
and CO2
- Succinyl CoA is converted to
Succinate in a reaction coupled to the
Phosphorylation GDP to give GTP
- Succinate is dehydrogenated
By FAD to give
Fumarate
- Oxidation of (S) - malate gives
Oxaloacetate, completing the
Cycle
- Fumarate undergoes
Conjugate addition of water
To its double bond to give
(S) -malate