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Nerve roots cross react with immune response GUILLAIN BARRE SYDNROME -…
Nerve roots cross react with immune response
GUILLAIN BARRE SYDNROME
molecular mimicry (1-3 W/ prior)
campylobacter jejuni (GIT) -> Diare
CBV, EBV --> ISPA
HIV
minor trigger (surgery, trauma, bone marrow transplant) to immunity
Demyelinasi (AIDP)
Acute immune mediated polyneuropathy
dysautonomia bila terkena ANS
urinary retention
tachycardia (Vagus)
aritmia
ortostatik hipotensi
sensory
pain & paresthesia
motor (Ascending pattern)
limb weakness, areflexia
phrenic N involvement
diaphragm paralysis
CN involvement
CN 3, 4, 6
MILLER FISHER
9,10,11,12
Dysphagia
Respiratory Faillure
IgG to gangliosides
Axonal (AMAN, AMSAN)
increase BV permeability
more protein in CSF