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PICO Question: In adult patients with major depressive disorder, does ECT…

- - - - PubMed (n = 72)
      - CINAHL (n = 48)
      - PsycINFO (n = 30)
      - Cochrane Library (n = 15)
      - Additional records identified through manual reference review (n = 14)
        Total records identified (n = 179)
  - - - Reasons for Exclusion
        
        Unrelated to ECT treatment
        
        Did not evaluate depressive symptoms
        
        Non-adult populations
        
        Editorials or opinion articles
        
        Non-comparative studies
  - - - Reasons for Exclusion
        
        Insufficient outcome data
        
        Poor methodological quality
        
        Intervention inconsistently implemented
        
        No antidepressant comparison group
        
        Outcomes unrelated to quality of life