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Altered Hormonal & Metabolic Dysfunction - Coggle Diagram
Altered Hormonal & Metabolic Dysfunction
SIADH (water balance)
Manifestations
hypoatremia
confusion
fluid retention
Diagnostics
concentrated (dark) urine
low Na+
Caused by
feedback impaired
ectopic production
too little ADH
Treatment
ADH blockers (medication)
fluid restriction
Hormonal dysfunction
Hypothyroidism
Caused by
too little hormone
increased TSH
underactive gland
Manifestations
weight gain
cold intolerance
fatigue
Diagnostics
high TSH
low t3/4
Treatment
hormone replacement therapy
Where
: thyroid
Cushing Syndrome (adrenal cortex)
Manifestations
"moon face"
hyperglycemia
truncal obesity
Diagnostics
high cortisol
Caused by
impaired negative feedback
possible ectopic ACTH
excessive cortisol
Treatment
removal of cause (tumor)
medication
Hyperthyroidism
Caused by
overactive gland
too much hormone
negative feedback suppressed
Manifestations
heat intolerance
tachycardia
weight loss
Diagnostics
high t3/4
low TSH
Treatment
surgery
antithyroid medication
radioactive iodine
Addisons Disease (adrenal)
Manifestations
hypotension
hyperpigmentation
Diagnostics
low cortisol
Caused by
gland failure
too little cortisol
increased ACTH
Treatment
hormone replacement
Disruptions in hormone regulation, production, or response
Diabetes insipidus (water loss)
Caused by
too little ADH
receptor/response issue
pituitary impairment
Manifestations
dehydration
polydipsia
polyuria
Diagnostics
dilute urine
Treatment
desmopressin
hydration
Disruptions in water/Na+ balance, and hormone-regulated metabolism