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Lipid Metabolism, HDL and VLDL, Apolipoprotein aids, liver, insulin,…
Lipid Metabolism
Lipid Transport
Peripheral Cholesterol Activity and Summary of Lipid Transport
HDL and VLDL
cyclic conversion
CETP cofactor
esterase enzyme
occurs to the chylomicron as well
purpose
transport HDL from blood into the cell
synthesize cholesterol
HDL releases a TG
Apolipoprotein aids
apoB-100
transport ldl into the tissue
apoC-II
vldl cleavage
ApoE
transport into liver
liver
removal
triglyceride and cholesterol
insulin
independent
muscle
dependendt
adipocytes
enzymes that decrease TG
Hepatic Lipase
IDL to LDL
LPL
VLDL to IDL
APOC-II
Lipo protein
lipid and protien
contents of HDL
surface
protein
esters
MTP
APO48
ER + TG
chilomicron
formation of cholesterol
cleave a TG from the DL
use to make VLDL
MTP upregulates
and Chiylomicron remnant
ApoE receptor
trabsport of IDL and CMR from blood to liver
LDL receptor
transport LDL
high TG
low density
LDL
high density relative to VLDL
micele
formed and brought into the enterocyte
chilomicron/vldl/ldl/idl/hdl formed
transport into the blood stream
break down by hpl or dl lipase
hdl remains
transport into the liver
formation of holesterol
different enzymes ised
high ldl
transport to the periphery
plaque in the vessel
asthersclerosis