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Alzheimer's Drugs - Coggle Diagram
Alzheimer's Drugs
Cholinesterase Inhibitors
Donepezil
Galantamine
Rivastigmine
Lifestyle factors
Dietary Factors
Vit. E
B12
Vitamin D
physical activity
mental stimulation
Monoclonal Antibodies
targets both soluble Aβ oligomers (mutated) and beta-amyloid plaques
Lecanemab
more selective for soluble amyloid oligomers
Aducanumab
targets ONLY mature beta-amyloid plaques
Donanemab
Lipid, cholesterol, blood glucose lowering drugs
Statin
GLP-1 Agonist
NMDA Inhibitors
Memantine
non-competitive inhibitor of the NMDA receptor (binds glutamate bound receptor)
acts analogously to Mg2+ blocking NMDA-mediated calcium influx (more potent)
NSAIDS