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Telomere Attrition & Cellular Aging (The primary driver of age-related…

- - - - Counteracts the "End-Replication Problem."
      - Active in stem cells; inactive in somatic cells.
      - Adds TTAGGG repeats to DNA ends.
- - - - Approach ...
        
        Test telomerase activator compounds in human cell cultures
        
        Then, measure length, stability, and markers of oncogenes