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Mutliple Sclerosis - Coggle Diagram
Mutliple Sclerosis
Reflexes
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Testing pathway from tendon to spinal cord
Simultaneous inhibition and excitation
Patellar reclex: inhibition of hamstring, excitation of quads
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Signs
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- Unilateral Visual loss
- Red vision affected first
- Pain on eye movement
- Pain does not last more than 2 weeks usually
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- Facial palsy
- Ataxia
- Diplopia
- Trigeminal neuralgia
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- Lhermitte's syndroome
- Numbness
- Urinary urgency
- Faecal incont
- Sexual dysfunction
- Spastic paraplegia
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Suptypes of MS
At least 24hr in abscene of infectino or other physiological stress
Often don't 100% resolve to baseline
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Symptoms
- FATIGUE
- Uthoff's phenomenon - heat intolerance
- Depression
- Neuropathic pain
- Urinary frequency
- Ambulatory dysfunction
- Spasm / spasticity
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DDx MS
- Migraines
- Functional neurological disorder
- Ischaemia
- Functional / psychogenic
- Inflammatory - sarcoid, lupus
- Infection - syphilis
- Nutritional
- Metabolic
- Genetic - fabry's disease
Where is the problem
- Brain
- Spinal cord
- Peripheral nerve
- NMJ
- Muscle
What is the problem
- Vacular
- Infectious
- Immune
- Traumatic
- Toxic
- Metabolic
- Genetic
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MS Definition
Immune mediated chronic inflammation disorder of the CNS
Characterised by sclerosis (hardening ) of multiple nerves in the CNS
Risk Factors for MS
- EBV
- Smoking
- Low vit D
- Genetics
- Adolescent obesity
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