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Advances in Non-Coding DNA Editing and Its Therapeutic Applications -…
Advances in Non-Coding DNA Editing and Its Therapeutic Applications
Introduction to Non-Coding DNA
Rôle and importance
Previously considered “junk DNA”
Now known to regulate gene expression , guide cellular behavior, and maintain genome stability
The Gene Editing Innovation
Development of a Smart Nano Particle Editing Tool
Targets regulatory sequences in non-coding DNA
Offers safe and precise modifications
Distinction from Conventional Technologies
Focuses on controlling gene activation and repression
Adresses 98% of the human genome responsible for gene regulation
Applications of the New Editing Tool
Medical and Therapeutic Uses
Curing cancer : CRISPR-based approaches
Potontiel to treat neurological disorders like Alzheimer’s
Modulating the immune system for autoimmune diseases
Preventing hereditary disease through gene suppression or activation
Components of the Tool
Guide RNA : directes the system to specific DNA locations
Enzyme: acts as a molecular scissor to cut, delete, replace, or modify DNA
Advantages
Precisely corrects or disables faulty instructions
Enables personalized medecine tailored to individual genetic profiles