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Antibiotcs - Coggle Diagram
Antibiotcs
Beta LActams
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Gram + - MSSA gram neg - MSS, resistance gram - Pseudomonas
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Side Effects
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Increased risk of C. diff. infection
Classics: Clindamycine, Quinilones, 3rd gen cephlasporins
- Hypersensitivity reactions
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Quinolones
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USe
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EAtypical causes Pneumonias - legionella, mycoplasma, chlamydia - in place of a macrolide
S/E
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- Tendonitis, ruptured achilles tendons
- Reduction in seizure thresholds
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- Black box warning - inceased risk of aneurysm fomation in aorta⬛
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Macrolides
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s/e
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- GI Intolerance esp erythro
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- Cholestatic jaundice with E. estolate (not stearate)
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Vancomycin
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USe
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MRSA infx - blood, endocarditis, bone
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Metronidazole
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s/e
- Disulfaram reaction - anti-booze
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Oxazolidinones
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S/e
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- Thrombocytopenia - longer time
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KEYS
Start Smart then focus
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- Relative systemic sickness
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Sulfa Drugs
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s/e
- 5-10% allergic - more in HIV setting
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- Stephens johnsons syndrome, erythema nodudum, e. multiforme, vasculitis
- Fever, headache, depression
- Hepatic necrosis, cholestatic jaundice
- High dose ass with crystalluria
- Acute haemolytic anaemia ass with G6PD deficiency
- Avoid in last timester - compete with binding sites on plasma albumin
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Chloramphenical
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S/E
- Anaemia, aplastic anaemia in nearly everyon
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- disulfaram reaction - Anti-booze
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