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Parkinson's Disease - Coggle Diagram
Parkinson's Disease
Risk factors
age >60yo
male
Pathophysiology
degeneration of dopaminergic neurons
dopamine deficiency in basal ganglia
slow gait initiation
slow movements
flat affect
shuffling gait
appearing older
fatigue
soft voice
imbalance between dopamine and acetylcholine
loss of inhibition within striatal circults
L hand tremor
poor RAM
loss of dopaminergic input to basal ganglia
shuffling
slow to intitate gait on command
increased falls (2)
wide based stance
Lewey body formation in motor and cognitive circuits
agitation
irritability
forgetfulness
autonomic dysfunction due to vagus involvement
slowed GI motility
constipation
weight loss
decreased appetite