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Chapter 19 and 27 - Coggle Diagram
Chapter 19 and 27
Chapter 27
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Impacts on Humans
Beneficial Prokaryotes:
Gut microbiota: digestion, vitamin production, intestinal development
Food industry: cheese, yogurt, fermented foods, beverages
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Bioremediation: oil spills, sewage treatment, radioactive cleanup
Bioplastics & biofuels: PHA production, ethanol from biomass
Pathogenic Bacteria:
Cause ~50% of human diseases (tuberculosis, diarrhea, Lyme disease)
Toxins:
Exotoxins → secreted, cause disease even if bacteria gone (e.g., cholera, botulism)
Endotoxins → released when bacteria die (e.g., Salmonella typhi)
Horizontal gene transfer spreads virulence → harmless bacteria → pathogens (e.g., E. coli O157:H7)
Antibiotic Resistance:
Rapid evolution + HGT → multidrug-resistant strains (MRSA, XDR-TB)
Discovery of new antibiotics (malacidins, teixobactin) using metagenomics
Human Applications: food, medicine, biotechnology, environmental solutions
Viruses cannot replicate independently. They lack ribosomes, enzymes, and ATP—they are obligate intracellular parasites.
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Viral Replicative Cycle
Steps of infection:
- Attachment: Virus binds to host cell.
- Entry: Genome enters (via injection, endocytosis, or membrane fusion).
- Hijacking host machinery: Viral genome takes over transcription, translation, replication.
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- Assembly: Viral proteins and nucleic acids self-assemble into new virions.
- Exit: New viruses leave (lysis or budding), spreading infection.
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Evolution of Viruses
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Likely evolved after cells existed, from mobile genetic elements:
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Large viruses like Mimivirus, Pandoravirus, Pithovirus blur the line between viruses and living cells—they even have some genes for translation and repair.
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