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Immune System - Coggle Diagram
Immune System
Concept of immunity
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Innate immunity: defense against any pathogen, immediate and non-specific
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Adaptive immunity: resistance to a specific pathogen, learned and memory-based
Innate immunity 2nd
phagocytic WBCs: macrophages, neutrophils, dendritic
inflammation results in redness, swlling and pain
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complement system leads to opsonization, inflammation, chemotaxis and lysis
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Innate immunity- 1st
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chemical defenses include antimicrobial peptides such as B cells, T cells and antibodies
Physical barriers include intanct skin, mucus membranes and normal microbiota
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Cellular Defenses
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Lymphocytes include B cells and T cells, B cell produce antibodies
WBCs include granulocytes: basophil, neutrophil and eosinophil
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Antibodies and Antigens
Antibodies (immunoglobulins) bind antigens and trigger mechanisms such as neutralization, complement activation and opsonization
Fiver major Ig classes: IgG, IgM, IgA, IgE, IgD
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Plasma protein mediators
acute-phase proteins include C-reactive protein (functions to coat bacteria, preparing them for ingestion by phagocytes), ferritin and transferrin (function to inhibit the growth of pathogens) and mannose-binding lectin (activates complement cascade)