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Immune System, Includes - Coggle Diagram

- - - - Myeloid Cells
        
        include
        
        Macrophages
        
        perform
        
        phagocytosis
        
        important against
        
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        can generate
        
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        expresses
        
        TLR-4
        
        recognizes
        
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        co-receptor
        
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        actiavetes
        
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        expresses
        
        Dectin-1
        
        recognized by
        
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        expresses
        
        Dectin-2
        
        expresses
        
        cGAS
        
        induces
        
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        recognized by
        
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        expresses
        
        RIG I
        
        recognized by
        
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        activated by
        
        IFN gamma
        
        include
        
        Dendritic cells
        
        include
        
        Granulocytes
        
        release
        
        includes
        
        mast cells
        
        store
        
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        express
        
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        act as
        
        Antigen Presenting Cells
        
        present on
        
        MHC I
        
        activates
        
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        present on
        
        MHC II
        
        activates
        
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        enhanced by
        
        Adjuvant
        
        perform
        
        extravasation
    - - PRRs
        
        recognize
        
        antimicrobial peptides
        
        include
        
        cGAS
        
        CLR
    - - Liver
        
        produces
      - Commensal bacteria
        
        produce
        
        Short chain fatty acids
        
        promote
        
        Tolerogenic dendritic cells
        
        support
        
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    - - skin
        
        contains
        
        chemical defenses
        
        include
        
        metalloproteases
    - - granulocytes
        
        include
        
        neutrophils
        
        produce
        
        NETs
        
        trigger
        
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    - - complement system
        
        triggered by
        
        Mannose Binding Lectin
- - - - B Cells
  - - - differentiates into
      - differentiates into
        
        T cells
        
        mature in
        
        Thymus
        
        AIRE
        
        central tolerance
        
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        express
        
        T cell receptor
        
        requires
        
        CD3
        
        undergo
        
        positive/negative selection
      - differentiates into
        
        NK cells
      - differentiates into
        
        ILCs
        
        respond to
        
        chemokines
  - - - performed by
        
        RAG1/RAG2
        
        failure leads to
        
        SCID