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Intro to Haematology - Coggle Diagram
Intro to Haematology
Signs of regeneration
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lack of regeneration = uniform, don't see marrow
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RBC morphology
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shear products (keratocytes, schistocytes, acanthocytes)
oxidative damage (Heinz bodies, eccentrocytes, pykknocytes)
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Reticulocytes
On a DiffQuik or Giesma stained smear, young cells containing ribosomal RNA show up as larger, bluer cells --> polychromatophils 
stain the same cells with New Methylene Blue, and the RNA precipitates forming aggregates/retiuculum--> reticulocytes
cat retics released as aggregate retics, maturing to punctate retics over time
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Left shift and toxicity
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regenerative left shift--> neutrophilia, segmented > bands
degenerative left shift--> neutropenia, bands > segmented
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Leukaemia
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Chronic
chronic lymphocytic leukaemia (CLL)--> lymphocytes appear small, mature
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