Interventions and leaders’ responses: 1st level is awareness and knowledge the health and normalcy by providing trainings and workshops. 2nd level is to observe microscopic changes and minute disturbances in its initial stages through screening tests, or offering questionnaires. 3rd level is to acknowledge the symptoms, and then diagnose the problem, discover the root causes, and do some treatment. 4th level is crisis management: save life, reverse the process of the disease, and restore function