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Viral Hepatitis, Hep A, Hep E - Coggle Diagram

- - - - SVR= No detectable virus in a blood sample 12 weeks after completion of treatment
  - - - Pegylated interferon
      - Ribavirin
    - - second generation of direct-acting antiviral (DAA)
- - - - Stable
      - Cirrhosis
        
        Slowly progressive
        
        Liver FAilure
        HCC
        Transplant
        Death
- - - - May no be pos until 6 months after infx
      - Detected by enzyme immunoassay
      - New combined antigen-antibody test
    - - Detected by molecular assay
      - Appears before antibodies
- - - - Measures hepatic elastography (liver stiffness)
      - USe
        
        Mild fibrosis and cirrhosis
      - Disadvantages
        
        Not good for moderate and severe fibrosis
    - - Coag - High INR
      - Low albumin
      - High bili
      - High LFTs
      - Low platelets
      - Low sodium
  - - - previous gold standard
      - Disadvantages
        
        Day ward admission
        
        Complications
        Bleeding
        Pain
        Pneumothorax
        Infx