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vaccines - Coggle Diagram
vaccines
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effects
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secondary (Anamneatic response)-memory B cells activated increasing the antibody titer producing a rapid intense secondary immune response
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Ideal vaccine
Swallowed instead of injected, lifelong immunity, stable without refrigeration, affordable, multiple antigen
Live attenuated-weakened pathogen can replicate ex MMR, Varicella, yellow fever, OPV pro: strong long lasting immunity Cons: not safe for immunocompromised refrigeration
Inactivated vaccines-pathogen killed by heat chem or radiation ex HPV, hepA, rabies Pros: cant cause disease safe Cons: weaker response boosters
Subunit, Recombinant, Polysaccharide, and Conjugate Vaccines - use specific pathogen parts to stimulate immunity ex HPV. hepB, pneumococcal, meningococcal Pro: safe effective targeted Cons boosters
Toxoid Vaccines-contain inactivated toxins(toxoids) from bacteria ex diphtheria, tetanus pro safe stable con boosters
mRNA- use mRNA that encodes a piece of the pathogen's protein ex Pfizer, Moderna pro fast design strong immune response con refridgeration new
Viral Vector- hamless virus deliver genetic material from pathogen ex J&J covid, Ebola pro strong and adaptable cons: preexisting immunity to vector may reduce effectiveness