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Yoselin Mora Period 3 Muscular System - Coggle Diagram

- - - - Molecular Composition of Myofilaments:
        -Thick Filaments: composed of protein myosin that contains 2 heavy and 4 light polypeptide chains
        -heavy chains interwine to form myosin tail
        -light chains form myosin globular head
        -During contraction heads link thick and thin filaments together, forming Cross Bridges
        -Myosins are offset from each other, resulting in staggered array of heads at different points along thick filament
        -Thin Filaments: composed of fibrous protein actin
        -Actin is a polypeptide made up of kidney-shaoed G actin (globular) sub units
        -G actin subunits bears active site for myosin head attachment during contraction
        -G action subunits link together to form long, fibrous F actin (filaments)
        -Z actin strands twist together to form thin filaments
        -Tropomyosin and Troponin: regulatory proteins bound to actin (control if cross bridge happens)
        -Other Proteins help form the structure of the myofibril
        
        -Elastic Filament: composed of protein titin
        -Holds thick filaments in place, helps recoil after stretch; resists excessive stretching
        -Dystrophin: link thin filaments to proteins of sarcolemma
        -Nebulin, Myomesin, C Proteins bind filaments together
        -Maintain alignment of sarcomere