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Neurotransmitters - Coggle Diagram

- - - - Locus Coeruleus
      - Lateral Tegmental Reticular Formation
    - - Increased SNS
      - Attention
      - Arousal
      - Diffuse throughout forebrain
    - - Increased K+ efflux out of cell
      - Hyperpolarization
    - - Metabotropic
        
        Alpha
        
        Beta
  - - - Substantia Nigra
      - Ventral Tegmental Area
        
        Executive Functioning
        
        Emotional Regulation
    - - Metabotropic
        
        Inhibitory
        
        D2-Like
        D2, D3, D4
        
        Excitatory
        
        D1-Like
        D1 and D5
    - - Nigrostriatal
        
        Motor Tract
        
        Parkinson's
      - Mesolimbic
        
        Motivation / Reward
        
        Schizophrenia
        
        Substance Abuse
      - Tuberoinfundibular
        
        Inhibits prolactin release
    - - Increased K+ efflux out of cell
      - Hyperpolarization
  - - - Raphe Nucleus of Pons
    - - Ionotropic
    - - Increased K+ efflux out of cell
      - Hyperpolarization
      - Inhibitory
    - - Regulates all brain function
      - Diffuse throughout forebrain
      - Inhibits impulsivity
- - - - CNS
    - - Peripheral
  - - - Suppress transmitter release
- - - - A = Iontropic
      - B = Metabotropic
    - - Increased Cl- influx into ICF
      - Hyperpolarization
    - - Low GABA
        
        Greater seizure risk
        
        More anxiety
      - Target for anticonvulsants and anti-anxiety treatments
  - - - NMDA
      - AMPA
      - Kainate
      - mGluR
    - - Glutamate Transporters
      - Converted to Glutamine
      - Converted by glutamate synthetase
    - - Apoptosis in Stroke
      - Memory Formation