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Animal Physiology Part 2 - Coggle Diagram
Animal Physiology Part 2
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The Immune System
Innate Immunity
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A form of defense common to all animals that is active immediately upon exposure to a pathogen and that is the same whether or not the pathogen has been encountered previously
Lysozyme
An enzyme that destroys bacterial cell walls; in mammals, it is found in sweat, tears, and saliva
Toll-like Receptor (TLR)
A membrane receptor on a phagocytic white blood cell that recognizes fragments of molecules common to a set of pathogens
Phagocytic Cell
Neutrophils
Neutrophils are phagocytic and tend to self-destruct as they destroy foreign invaders, limiting their life span to a few days
Macrophages
A phagocytic cell present in many tissues that functions in innate immunity by destroying microorganisms and in acquired immunity as an antigen-presenting cell
Eosinophils
A phagocytic cell present in many tissues that functions in innate immunity by destroying microorganisms and in acquired immunity as an antigen-presenting cell
Dendritic Cells
An antigen-presenting cell, located mainly in lymphatic tissues and skin, that is particularly efficient in presenting antigens to helper T cells, thereby initiating a primary immune response
Natural Killer Cells
A type of white blood cell that can kill tumor cells and virus-infected cells as part of innate immunity
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Inflammatory Response
An innate immune defense triggered by physical injury or infection of tissue involving the release of substances that promote swelling, enhance the infiltration of white blood cells, and aid in tissue repair and destruction of invading pathogens
Adaptive Immunity
A vertebrate-specific defense that is mediated by B lymphocytes (B cells) and T lymphocytes (T cells) and that exhibits specificity, memory, and self-nonself recognition; also called acquired immunity
Lymphocytes
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B Cells
The lymphocytes that complete their development in the bone marrow and become effector cells for the humoral immune response
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T Cells
The class of lymphocytes that mature in the thymus; they include both effector cells for the cell-mediated immune response and helper cells required for both branches of adaptive immunity
B or T Cell Response
Antigen
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Epitope
A small, accessible region of an antigen to which an antigen receptor or antibody binds
Helper T Cell
A type of T cell that, when activated, secretes cytokines that promote the response of B cells (humoral response) and cytotoxic T cells (cell-mediated response) to antigens
Cytotoxic T Cell
A type of lymphocyte that, when activated, kills infected cells as well as certain cancer cells and transplanted cells
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Types of Immunity
Humoral Immune Response
The branch of adaptive immunity that involves the activation of B cells and that leads to the production of antibodies, which defend against bacteria and viruses in body fluids
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Immunization
The process of generating a state of immunity by artificial means. In vaccination, an inactive or weakened form of a pathogen is administered, inducing B and T cell responses and immunological memory. In passive immunization, antibodies specific for a particular pathogen are administered, conferring immediate but temporary protection
Monoclonal antibodies
Any of a preparation of antibodies that have been produced by a single clone of cultured cells and thus are all specific for the same epitope