Please enable JavaScript.

Coggle requires JavaScript to display documents.

(Updated) EPQ Plan - Coggle Diagram

- - - - Transition into how CRISPR-Cas9 could “supercharge” them by giving them programmable precision.
        
        Highlight the appeal: potentially targeted, self-replicating, and less disruptive to the microbiome than broad-spectrum antibiotics.
  - - - Clearly state my research question; frame it as an open debate: “This essay will explore to what extent CRISPR-Cas9-modified bacteriophages could provide a viable,
  - - - Pose a provocative question: “What if the greatest medical breakthrough of the 21st century came from a virus?”
- - - - 4.2 Effectiveness Against AMR - Evidence from lab studies and animal models.
        Case studies (e.g., compassionate use cases like Isabelle Carnell-Holdaway)
        
        4.3 Advantages - Specificity to harmful bacteria, minimal effect on microbiome.
        Self-replication and potential to overcome resistance
        
        4.4 Limitations / Challenges - Technical challenges in designing CRISPR-phages.
        Safety concerns and regulatory hurdles. Potential for bacterial resistance to phages
        
        4.5 Ethical and Practical Considerations - Compassionate use vs. mass application.
        Cost, accessibility, and global health implications