Please enable JavaScript.
Coggle requires JavaScript to display documents.
T-Cell Stem Cell, Il-4, IFN-y, RAG 1&2 TdT, Bone Marrow, ALLERGIES …
T-Cell
Stem Cell
Double Negative CD4-/CD8-
(PRO-T Cell)
Pre-T Cell (Pre-TCR)
Double Positive (CD4+/CD8+)
Immature T Cell
Positive Selection
to MHC I or MHC II
Yes
Moderate Binding
IL-2 aids in differentiation
Mature CD4
Mature CD8
Negative Selection
Central Tolerance
Moderate
Mature Naive T-Cells
1 more item...
Strong Binding
Death
LACK of AIRE (Autoreactivity)
APS1
No
T-Cell Death
a chain (aka light chain)
Rearrangement
B chain (aka heavy chain)
Rearrangement
Il-4
IFN-y
RAG 1&2
TdT
Bone Marrow
ALLERGIES
Eosinophils
B Cells
Smooth Muscle
Neutrophil (mucosal surfaces)
B Cell
Stromal and epithelial cells
Macrophage
T cell
Dendritic Cell
Remain in Lymph node
V-DJ
VJ
THYMUS
Cortical
Medulla