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Irritable Bowel Syndrome - Coggle Diagram

- - - - Visceral Hypersensitivy
        
        Abnormal GI Motility
        
        Delayed transit: (IBS-C)
        
        Alternating pattern: (IBS-M)
        
        Accelerated transit: IBS-
        
        Altered intestinal microbiome
        
        dysbiosis
        
        small intestinal bacterial overgrowth
        
        Mucosal Immune Activation and inflammatio
        
        3 more items...
        
        :arrow_down: pain threshold: abd pain from normal BMs
      - Disrupted signaling between CNS and ENS
- - - - Specialized care (GI or behavioral therapy)
      - Medications
      - Transportation difficulties
      - Healthy food
  - - - Dietary triggers
      - Medication regimens
      - Stress reduction
- - - - Cara Care
      - Bowelle
- - - - Antidiarrheals
        
        Loperamide
        
        Diphenoxylate/atropine
      - Anti-spasmodics
        
        Dicyclomine
        
        Hyosycamine
        
        Peppermint oil
      - Antibiotics
        
        Rifaxamin
      - 5-HT3 antagonists
        
        Alosetron
      - Mixed opioid receptor agonist/antagonist
        
        Eluxadoline
    - - Laxatives
        
        Osmotics
        
        Stimulants
      - Chloride channel activators
        
        Lubiprostone
      - Guanylate cyclase receptor activators
        
        Linaclotide
        
        Plecanatide
  - - - Low FODMAP: https://medlineplus.gov/ency/patientinstructions/000984.htm
      - Reduce caffeine intake
      - Reduce alcohol intake
- - - - Medications that cause diarrhea: antiarrhythmics, antihypertensives, cholesterol-lowing meds, diuretics, antianxiety meds, antiparkinsonian drugs, oral hypoglycemia agents, thyroid replacement, antacids, laxatives, NSAIDs, antibiotics, antineoplastics, magnesium supplements
      - Medications that cause constipation: anticholinergics, iron supplements, aluminum antacids, opiates, CCBs, vinca alkaloids, 5HT3 antagonists, GLP-1 agonists
  - - - CBC w/diff, chemistries, electrolytes, ESR, UA
    - - FCP or CRP, stool testing for infectious cause, serologic testing for celiac