Please enable JavaScript.
Coggle requires JavaScript to display documents.
Multiple Sclerosis (MS) - Coggle Diagram
Multiple Sclerosis (MS)
Pathophysiological Processes
Demylenation
oligodendrocyte damage
mylein loss
impaired saltatory conduction
Axonal Damage
neurodegeneration overtime
loss of neuronal communication
Immune Response
T cells and B cells cross the blood brain barrier
autoimmune attack on myelin sheath
Inflammation
plaque formation in CNS
Impact on CNS function
disrupted motor, sensory, or cognitive functions
slowed or blocked nerve impulses
Clinical Manifestations in Sarahs case
Cognitive
memory problems
difficulty concentrating
General
fatigue
Motor
spasticity
poor coordination
muscle weakness
balance issues
Relapsing-Remitting MS
Remissions
periods of partial recovery
Impact on daily life
unpredictable functioning
Exacerbations
symptom flare ups
Sensory
tingling
blurred/double vision
numbness
optic neuritis
Diagnostic findings
CSF
oligoclonal bands, elevated IgG
evoked potentials
delayed responses
MRI
plaques/lesions in white matter
Treatment Strategies
Symptom Management
spasticity
baclofen
fatigue
amantidine, energy conservation
vision loss
corticosteroids for acute relapses
Rehabilition
OT
cognitive therapy
PT
Disease Modifying Therapies (DMTs)
glatiramer acetate
ocrelizumab
interferon-beta
Lifestyle
healthy diet
stress reduction
exercise
Complications
Depression/Anxiety
Increased Risk of Infections
Cognitive Decline
Mobility Loss
wheelchair dependence