Please enable JavaScript.

Coggle requires JavaScript to display documents.

Sickle Cell - Coggle Diagram

- - - - Antimicrobials
      - PE
      - Pulmonary oedema
    - - Top up transfusion
      - Red cell exchange RCE
    - - Additional disease modification required
        
        Blood transfusion programm
        Exchange vs Transfusion
      - Potential candidate for curative therapy
- - - - Within 30 min
  - - - FBC & retics
      - RLB
      - LDH
      - CRP
      - G&S
      - Septic screen
    - - Resp viral swap if appropraite
      - MSU
    - - CXR
- - - - Emergency Rec cell Exchange
      - Vascath insertion
      - RCE for HbS < 30%
      - Bloods post exchanng
      - Apspirin - held in view of haemorrhagic
      - Not suitable for thrombolysis
    - - RCE programme via dual lumen vortex port
      - Aspirin
      - Consider bone marrow transplant - sibling match?
- - - - Endothelial dysfunction
        
        Free heme - tocis
        
        Sterile inflammation
    - - Vaso-occulusion
        
        Ischaemic reperfusoin injury
- - - - Simple
      - Red cell exchange
    - - Not recommended in uncomplicated painful crisi as there is no evidence that it shortens the duration of the painful crisis