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thermoreceptor detects decrease in body temp, adipose insulation, surface…
thermoreceptor detects decrease in body temp
afferent nerves
thermoregulatory control centre in hypothalamus
heat gain centre activated and heat loss centre inhibited
increased sympathetic nervous system activation
norepinephrine acts at alpha 2 receptors
cutaneous vasoconstriction
homeostatic response decreases heat loss
radiative, conductive and convective heat loss
nor/epinephrine induced beta adrenergic receptor stimulation
white adipose
lipolysis > NEFAs
fuel
skeletal muscle
glycogenolysis > glucose
venous shunting (countercurrent exchange system)
stimulation of cardiac beta 1 adrenergic receptors
increased heart rate and pulse rate
somatic nervous system
skeletal muscles, shivering
dermal thermoreceptors detect temperature decrease
increased mitochondrial ROS
increased Rho kinase
inhibition of myosin light chain phosphatase
alpha 2 receptor upregulation
adipose insulation
surface area to body mass ratio