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Melanoma - Coggle Diagram
Melanoma
Risk Factors
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- Number of pigmented lesions / nevi
- Dysplastic nevi - precursor
- PRevious melanoma (10x increased risk of second primary)
- Hereditary
Melanocortin - 1 receptor (linked ot preople with red hair / photosensitivity)
CDKN2A
CDK4 gene mismatch
- Severe sunburn / UV exposure
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Subtypes
- Superficial spreading 70%
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Imaging
NCCN - ROutine imaging not recommended for non-met sentinel lymph node negative disease <2mm in Breslow depth
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Diagnosis
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Seven Point Checklist
Major features
Change in
- Colour
- Size
- Shape
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Adjuvant Therapy
Indications
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- In transit or satellite lesions
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Prognosis
Prognostic features
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- Inverse correlaition with thickness / ulceration
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