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Negative + Positive Feedback loops, mechanisms amplify a physiological…
Negative + Positive Feedback loops
negative
negative feedback + control systems
Optimum = factor within the normal range
receptors detect stimulus -- stimulus -> effector-> response
Optimum - factor back at normal range
receptors detect stimulus -- stimulus -> effector-> response
return to optimum again
positive
Optimum = factor within the normal range
normal fluctuations in temp - (around set point)
pathogen detected - macrophages attack and release interleukins which stimulate hypothalamus - body temp rises because of increase in prostaglandin production causing shiver
fever peaks and body temp then falls
reset temp to optimum
fever - positive feedback - response escalation
mechanisms amplify a physiological response to achieve particular outcome
pathogen enters body
positive feedback = large deviation from normal
infection subsides - ending positive feedback escalation
mechanisms stabilise body back to steady state - induce counter response
stimuli causes factor to change from homeostasis
bring factor back to homeostasis
stimuli causes factor to change from homeostasis
acts to bring factor back to homeostasis
REFERENCES - BIOZONE