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Adaptive immune response to an infection, Immune memory to sars-cov-2 -…
Adaptive immune response to an infection
Innate immune response to I.e. Sars-Cov infection: dendritic cell activation and uptake of pathogens
Induction of adaptive immunity
Treg: regulation of inflammation
CTL (cytotoxic t lymfocyte): killing of infected cells
Th cytokine production
Th1: Stimulate antigen presentation, Stimulate cytotoxic CD8+ cells
CD8+ cells undergoes assymetric division
Each CD8+ cell gives rise to one effector T cell and one memory T cell
Tfh: induction of antibodies
B-cell
Plasma cell
Production of antibodies (IgG, IgM)
memory cells
Eventually help in the establishment of a pool of memory B-cells
Also important for support of the B-cell isotype switch
Myeolid cDC1: Activates Cytotoxic CD8+ T-cells, Cross presentation of viral antigens to Th1 cells.
Myeloid cDC2 cells: Activation of Th cells, mainly Th2, Th17, Treg
pDC: Anti-viral response> production of large amounts of Interferons
Immune memory to sars-cov-2
Memory B-cell
Memory T-cells