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Chapter 14 and 15 - Coggle Diagram

- - - - Codominant IA/IB -> AB type
- - - - True‑breeding -> hybridization (P -> F1 -> F2)
  - - - Monohybrid 3 : 1 phenotype ratio
  - - - Dihybrid 9 : 3 : 3 : 1 ratio
  - - - Homozygous vs heterozygous, phenotype vs genotype
  - - - Example: 1/2 × 1/2 = 1/4 (double‑recessive)
    - - Example: P(heterozygous) = 1/4 + 1/4 = 1/2
- - - - Trisomy 21 (Down), XXY (Klinefelter), XO (Turner), XYY, XXX
  - - - Cri‑du‑chat (5p deletion)
      - Philadelphia chromosome -> CML
  - - - Disorders: LHON, mitochondrial myopathy
- - - - Morgan’s white‑eye mutant on X in fruit flies
  - - - Barr body, mosaic expression, XIST RNA
  - - - Parental > recombinant frequency
    - - Recombination frequency -> map units 
      - Sturtevant’s linkage maps