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White Blood Cells - Coggle Diagram

- - - - nucleus with two to five lobes
        
        the number increasing with the age of the cell
        
        polymorphonuclear
      - 10–12 µm in diameter
      - release
        prostaglandins
        
        increase blood flow and vascular permeability
        
        allowing the passage of exudate into the damaged
        area
        
        causing inflammation
      - Secret leukotrienes
        
        attract other phagocytes to the site of infection
      - life span of around 10 hours
        
        can be shortened when they are actively engulfing
        
        death of neutrophils in large numbers forms purulent
        necrosis
        
        Pus
  - - - Arise from the lymphoid stem cell line
      - Much of their development and reproduction occurs in the lymphatic tissues
      - second most common type of leukocyte
        
        20-30%
      - Three size classes
        
        large cells are 10–14 µm
        
        smaller nucleus-to-cytoplasm ratio
        
        smaller cells are 6–9 µm
        
        larger volume of nucleus to cytoplasm
        
        cells that fall outside these ranges at 14–17 µm
      - Abnormally high counts
        
        characteristic of viral infections as well as some types of cancer
      - Abnormally low lymphocyte counts
        
        characteristic of chronic illness or immunosuppression
        
        including that caused by HIV infection and drug therapies that often involve steroids