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Red Blood Cells - Coggle Diagram
Red Blood Cells
Haemoglobin
Affinity for oxygen
Changes under certain conditions
Affected by
2,3 diphosphoglycerate concentration
2,3 DPG
Plentiful in erythrocytes
Bi-product of red
cell glycolysis
highly charged anion
Binds to the b chains of deoxyhaemoglobin
An increase
shifts the oxygen dissociation curve to the right
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Induce a tense state
Commonly caused by:
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stored blood in a blood bank has decreasing 2,3
DPG levels over time
less
effective at releasing oxygen to the tissues
oxygen dissociation
curve shifts to the left.
pH
Bohr effect
When the pH falls
CO2 increases in the tissues
carbonic acid
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Decrease Hb affinity for oxygen
Increases its tendency to bind hydrogen ions
More due to the acidification
more deoxyhaemoglobin
Improves oxygen delivery where it is needed
Dissociation curve shifts to the right