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GI TBL 5 and 6 - Liver - Coggle Diagram

- - - - Closest to vascular core - receive highest concentrations of O2 and solutes
      - More resistanct to cell injury, chronic viral hepatitis
    - - Closest to central vein, lowest concentration of O2 and nutrients
      - Liver destruction in alcoholic cirrhosis, aflatoxin
- - - - Healthy person develops both HBsAg and IgM anti-HDV Ab
    - - Develops cirrhosis within 2-3 years
        Acute - active ADV replication and suppression of HBV with high ALY levels
        Chronic phase - HDV replication decreases, HBV replication increases, ALT levels fluctuate - progresses to cirrhosis and HCC