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Anxiolytic and Hypnotic Drugs - Coggle Diagram
Anxiolytic and Hypnotic Drugs
BENZODIAZEPINES
Bind to γ-aminobutyric acid (GABAA) receptors.
GABA is the main inhibitory neurotransmitter in the CNS
Benzodiazepines increase the frequency of chloride channel opening produced by GABA.
The influx of chloride causes hyperpolarization, that moves the postsynaptic potential away from its firing threshold inhibiting formation of action potentials
Alprazolam
Chlordiazepoxide
Clonazepam
Clorazepate
Diazepam
Estazolam
Flurazepam
Lorazepam
Midazolam
Oxazepam
Quazepam
Temazepam
Triazolam
BARBITURATES
Bind to GABAA receptors enhancing GABA transmission by prolonging the duration of chloride channel opening. Also Block excitatory glutamate receptors. These molecular actions lead to decreased neuronal activity.
Amobarbital
Pentobarbital
Phenobarbital
Secobarbital
Thiopental
OTHER HYPNOTIC AGENTS
Antihistamines
Zaleplon
Doxepin
Eszopiclone
Ramelteon
Zolpidem
OTHER ANXIOLYTIC DRUGS
Antidepressants
Buspirone
BENZODIAZEPINE ANTAGONIST
Flumazenil