------------------------ pan diabetes, painless icterus, asc Cholangitis, epigas pain, throbophelebitis, portal HTN
------------------------ age, smoke, alcohol, ch pan, diabetes, :explode: K-RAS / :forbidden: P16 (CDK inhibitor), TP53
Ductal AdenoCa: very Agg, poor prog, CZ 1st in the world / preMalig: PanIN - IPMN - MCN
------------------------ often in Kaput, solid, not sharp, infil pan ducts > obst & stasis , peritoneal carcinosis
------------------------ well-medium-lowly diff glandular / tubular structure w/ high mucus production