Chapter 14: Systems Thinking: From Single Solutions to One Health

Introduction to Systems Thinking

usefulness of reductionist thinking

science-based disciplines

complexity of problems

population perspective

systems thinking as a complement

reductionist thinking

looks at 1 fact or variable at a time

reduces the problem to one potential "cause" and one "effect"

"magic bullet" or "miracle cure" approach

one answer to improve outcomes

Effective for specific factors like contributory causes of disease

Builds on reductionist thinking, not replacing it

As problems become more complex, need to evaluate all factors and their interconnections

Understanding Systems

what is a system?

O'Connor & McDermott: Systems maintain existence through the interaction of parts (ex: the human body)

Systems VS Heap

Definition: An interacting group of items forming a unified whole

A system has interconnected parts, while a heap is just a collection

Changes in a system affect its structure; arrangement is irrelevant in a heap

Behavior Depends on Structure: A system's behavior is determined by the overall structure

Systems Thinking in Population Health

Steps for Complete Systems Analysis

Systems thinking applied to health

tools for system analysis

Population health has shifted toward systems thinking

Diagrams/Graphics: Visual tools to represent systems

Initial 3 Steps in Systems Analysis

  1. identify key influences/interventions of an outcome
  1. indicate the relative strength of each influence
  1. determine how influences interact when more than one is present

dynamic approach

additional steps in systems analysis

Complex Systems: Systems rely on feedback loops to maintain stability

Feedback Loops: Positive or negative impacts on outcomes

Bottlenecks: Identify points where systems are slowed down

Leverage Points: Identify opportunities for major improvements in outcomes

  1. Identify dynamic changes through feedback loops
  1. Identify bottlenecks that limit effectiveness
  1. Identify leverage points to improve outcomes

One Health Approach

Systems Diagrams

Health Disparities and Systems Thinking

Applying Systems Thinking to Population Health

How to Use System Diagrams

(+) or (-) signs indicate whether factors increase or decrease subsequent outcomes

Arrows indicate relationships between factors

Five Key Questions for Systems Thinking

  1. How can systems thinking incorporate interactions between factors to understand disease etiology?
  1. How does it account for interactions between diseases?
  1. How can it help identify bottlenecks and leverage points for health improvement?
  1. How can it help develop strategies for simultaneous interventions?
  1. How does it help look at processes as a whole for better intervention planning?

Example Applications


Social Determinants of Health: Understanding the broad impact of societal factors

Syndemics: The interaction of multiple diseases, like HIV leading to other conditions

One Health Initiative


Global Factors Affecting Health


What is One Health?


Historical Context: Rudolph Virchow coined "zoonotic disease," which is transmitted from animals to humans (e.g., anthrax, SARS, HIV)

Interconnection between human health, animal health, and ecosystem health

The rise of RNA viruses (e.g., HIV, SARS, COVID-19) and antibiotic resistance

Human Health Linked to Animal Health: Health threats can cross species barriers, and ecological changes impact disease transmission

Environmental change, population growth, and economic disparities accelerate disease spread.

Addresses microbiological changes, antibiotic resistance, population changes, and ecosystem shifts

importance of interconnectedness in addressing health threats and diseases

Barriers in Health Disparities Research

Systems Thinking and Modeling


Benefits of Systems Approaches


Challenges and Limitations


Future of Systems Approaches


Traditional analytical methods focus on independent effects, limiting the scope of research

Systems thinking allows for a more comprehensive understanding of health disparities

Formal Models and Simulations: Test and refine conceptual models

Identifying Intervention Points: Understanding underlying dynamics

Visualizing Dynamic Processes: Helps to explore complex interactions

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Stimulates innovation in research.

Generates new research questions.

Provides learning opportunities for stakeholders.

Contrasts alternative hypotheses for causes of health disparities.

Systems approaches complement, but don’t replace, traditional methods

Models should answer meaningful questions, not just serve as simulations

Focus on how dynamic factors at different levels contribute to health disparities

Shift from partitioning individual vs. group effects to understanding interconnections

Systems thinking leads to clearer, more actionable policies