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Bio: Blood - transports nutrient, defend against pathogen, regulates temp …
Bio:
Blood
- transports nutrient, defend against pathogen, regulates temp
Formed Elements - produced in cells in bone marrow
WBC - nucleus, lack hemoglobin, fights infection
found in blood, tissue fluid and lymph nodes
Disorders
Luekemia
produces excessive WBC in. marrow some are defective; crowds out RBC and platelets
Viniscrine derived from Vinca flower, vinca kills cell division
Infectious mononu
DNA herpes-type attacks B lymphocytes
AIDS
virus infects WBC, hurts immune system
RBC
Biconcave shape for flexibility to move oxygen easier
no nucleus
Carries : oxygen, c02, & hemoglobin protein (90 - 120 day life span)
Anemia
not enough RBC's
Iron is recycled from old RBC's
Causes :
not enough hemoglobin
diabetes
inflammatory diseases 9 arthritis HIV)
bad kidney cus it produces EPO = more RBC's
EPO
- enhances endurance, high altitudes produces more
Malaria
: parasite for RBC's
treatments - drugs
Sickle cell - genetic, altered shape of rbc
treatments drugs
Platelets
- stick to themselves and everything to form a clump to stop blood
vit K one job is to clot blood
Cascade
Thromboplastin(liver created) - converts fibrinogen into fibrin,
Fibrinogen protein(liver created) - fibrin threads sticky molecule
Clotting Disorders
Few Platelets
Leukemia, Radiation,
Diseases: ITP - immune system destroys platelets
few clotting factors
Liver Damage,
defective clotting factors
Hemophilia A - 1/5,000 male births 1/25 million female births
Heterozygous hemophilia extends human life span for hemophiliacs
Treatments: injections of clotting factors
Blood typing RBC
Immune system
antibodies - alarm to send microphages to fight recognizable disease
antigen - we have already
type A blood has A antigen types ab has both a & b antigen
ppl with the same antigen can donate to eachother
85% have
RH factor
antigen
Hemolytic disease - Male rh postive and mother is negative
the mothers rh antibodies will attack the babies rh antigens
causes jaundice in chidren
Treatments:
RHOGAM - covers mothers RH antibodies
Donation
AB+ universal reciever
O- universal donor
same anitbodies and same antigens cannot mix
Converting blood types
sugar enzymes can remove antigens (converts O but not RH factor)
ABO and RH are only 2 out of 33 blood types
only important in organ transplant, paternity tests, forensic science