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DNA - Coggle Diagram

- - - - LET: local E deposition/ length
        
        Photons, Protons: 30-40% complex DNA lesions
        
        SSB: sister chromatid template
        
        Heavy ions: >90% complex DNA lesions
        
        DSB: no templates
        
        Clustered DSB: two or more lesions within 10–20 bp (~1–2 helical turns of the DNA).
        
        Ineffective repair for DSB:
        HR repair is usually accurate in the DSB repair region, but associated crossover events pose significant risks of translocations, inversions, deletions
        
        Cell death
        
        2 more items...
  - - - OER: dose hypoxia/ dose in air to produce the same biologic effect
        
        ⬇️ O2, ⬆️ radioresistent
    - - 1min
    - - 30mins
    - - 10hrs
    - - 2hrs
  - - - ⬆️ shoulder ⬆️ repair ⬆️ radioresistent
  - - - Releasing contents