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Topic 11 :unamused: - Coggle Diagram
Topic 11 :unamused:
Two systems
Lungs
C02
From the tissues C02 starts its journey
Bound to Hb (12%)
Carbaminohemoglobin
Converted into HC03 and H+ (80%)
C02 finds H20 in RBCs
Carbonic anhydrase coverts to HC03 and H+
HC03- moves out of the cell
Extra H+ binds to Hb
Buffer Systems
Cl- moves into the cell (keep it neutral)
Chloride Shift
Dissolved in Plasma (8%)
Kidneys
2 Roles
normal regulation of HC03 in blood
fixed acid excretion
HC03
important blood base
Types of acid
Fixed/nonvolatile
cannot be converted into a gas
must be excreted by the kidneys
Lactic Acidosis/Ketoacidosis
Volatile
can be converted from a liquid for to a gaseous form to facilitate excretion
H2C03
Carbonic Acid
lungs
Buffering systems
protect the body from major swings in pH
Hb plays a major role
Numbers
Anion Gap
Normal: 9-14mEq/L
AG = [Na+] - ([Cl-]+ [HC03])
source of metabolic acidosis
fixed acid buildup
Excessive loss of HC03-
Base Excess
. >+2 = metabolic alkalosis
+/- 2
< -2 = metabolic acidosis
Acid/Base Balance
What does that mean?
Keep the pH in normal range
Normal range 7.35 to 7.45
more acid [H+] = lower pH