Please enable JavaScript.
Coggle requires JavaScript to display documents.
COVID-19 pandemic - Coggle Diagram
COVID-19 pandemic
Pathogenesis
Structural proteins enable the virus to access to host cells
S
Heavily N-glycosilated
N
Bind viral genome with NSP3 protein of the RTC
Packages RNA species
Produced during infection
Into viral particles
M
Dimer in the viron
Maintain the shape
E
Transmemmbrane protein
With an Ion channel activity
HE
enhances the S protein binding activity and spread of the virus through the mucosa
Clinical manifestations
Respiratory tract disease
Mild to severe
Risk factors for hospitalization and severe disease6
Obesity
Smoke
Infection less likely
More severe when infection is acquired
65 years or older
Fever
Cough
Dyspnea
tachypnea
Gastrointestinal symptoms
Taste alterations
Olfactory disturbances
Less presented
Cutaneous manifestations
Eryhtematous rashes
Urticaria
compromised cardiovascular system
Venous and arterial thrombotic events
Pulmonary Embolisms
Altered conscious state
Dizzines
Acute cerebrovascular disease
liver injury
Related with drugs
Hepatotoxicity
Related with cytokine storm
Immune-mediated damage
Multisystem Inflammatory Syndrome in Children
Opthalmological
Ocular pain
Redness
Follicular conjunctivitis
Headache
Coryza
Sore throat
Myalgia
Cyanosis
Hypoxia
Malaise