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Renoprotective action GLP-1 Receptor Agonists - Coggle Diagram
Renoprotective action GLP-1 Receptor Agonists
Reduction in Albuminuria
Reduces proteinuria (albumin-to-creatinine ratio)
Slows the progression of diabetic kidney disease (DKD)
Decreases albumin leakage through the glomerulus
Improvement in Renal Hemodynamics
Improves renal blood flow
Promotes natriuresis (increased sodium excretion)
Reduces glomerular hyperfiltration
Lowers intraglomerular pressure
Blood Pressure Reduction
Anti-Inflammatory Effects
Decreases inflammatory markers (e.g., C-reactive protein, TNF-α)
Lowers oxidative stress
Reduces renal inflammation
Anti-Fibrotic Effects
Reduces renal fibrosis
Prevents long-term scarring and damage to the kidneys
Inhibits activation of fibroblast growth factors
Prevention of Kidney Disease Progression
Protects against the onset of end-stage renal disease (ESRD)
Delays the need for dialysis or kidney transplantation
Slows the decline of glomerular filtration rate (GFR)