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Carlsson - Coggle Diagram
Carlsson
-
-
Thalamus
-
Indirect
Pathway through Thalamus
=hyperdopaminergia and
hypoglutamatergia reduces
protective influence of thalamus
=positive symptoms
Direct Pathway
=abnormal dopamine
and glutamate activity
excites thalamus,
starving cerebral cortex
of stimulation
=negative symptoms
Dopamine
-
there may also
be interactions
with other NTs
like serotonin,
glutamate, and
noradrenaline
-
Review Article
=2000
=evidence for
and against dopamine
hypothesis
=look beyond dop hyp
=look at specific brain
areas
=use info to produce
new anti psychotic
drugs that are more
effective with fewer side
effects
=literature review