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Autonomic Nervous System: Adrenergic and Cholinergic - Coggle Diagram
Autonomic Nervous System: Adrenergic and Cholinergic
Adrenergic
Associated with SNS
Sympathetic Nervous System
"Fight or Flight" Response
Adrenergic Antagonist
Sympatholytics
Adrenergic Agonist
AKA:Sympathomimetics
Can be...
Indirect acting
Direct acting
Mixd acting
Mimic effects of catecholamine (epi, norepi and dopamine)
Catecholamine is metabolized by MAO and COMT
Indicators
Bronchodilators
Nasal decongestants
Opthalamics
Cardiovascular failure or shock
Drugs
Dobutamine
Beta 1, increase cardiac output, IV drug
Epinepherene
Alfa and Beta, for anaphylactic shock and cardiac life support
Midodrine
Alfa 1, prodrug of Desglymidodrine, used for orthostatic hypotension
Norepinepherene
Alfa and Beta 1, vasoconstrictor, used for hypotension and shock
Phenylephrine
Alfa, primarily for short term increase of bp in shock, also used as a decongestant
Adrenergic receptors
Alfa-adrenergic
1
Postsynaptic effector cells
2
Presynaptic nerve terminals
Beta-adrenergic
2
Smooth muscle of bronchioles, arterioles and visceral organs
1
Heart
Dromotropic
Increase conduction through AV node
Chromotropic
Increase heart rate
Inotropic
Increase force of contraction
Both 1 and 2 are postsynaptic
Dopaminergic
Dialation of renal, mesenteric, coronary and cerebral vessels
Cholinergic
Associated with PNS
Parasympathetic Nervous System
"Rest and Digest" Response
Cholinergic Agonist
Parasympathomimetic
Cholinergic Antagonist
Parasympatholytic