Please enable JavaScript.
Coggle requires JavaScript to display documents.
The cell membrane, receptors and their functions, Membrane protein…
The cell membrane, receptors and their functions
-
-
-
-
Lipids: phospholipids, glycosphingolipids and cholesterol. Makes membranes fluid and hydrophobic
-
Carbohydrates: glycoproteins and glycolipids. Carbs get tagged for recognition which helps with binding to the ECM, shows what cell type it is
Membranes solidify (decrease fluidity) at colder temperatures.
To maintain fluidity these changes are made: increase the number of unsaturated tails (bent tails), decrease the length of the fatty acid tail and adjust the cholesterol content
At body temperature, cholesterol will decrease fluidity
At colder temperatures, cholesterol will increase fluidity
-
Helical bundles (integral) are used for enzymes, transporters and receptors
Beta barrel proteins (integral) are used for transporters (channel proteins)--openings or pores in the protein
Periperhal proteins are used for enzymes, anchorage (binds to ECM) and transporters (carriers)
-
Cell junctions
Tight junctions: membranes of neighboring cells are pressed together preventing leakage of the extracellular fluid These are leak proof
Desmosomes: Fasten cells together into strong sheets, these are not leak proof, but more for stretching like skin and muscles
Gap junctions: Communicating junctions, provide cytoplasmic channels between adjacent cells (pores and holes in them to communicate quickly). This is important roll for cardiac muscles. These have a lot of gap junctions so that the muscles can all contract at the same time